Principles of Sample Size Calculation
Completion requirements
View
1. Introduction
(This section is organised in the form of a book, please follow the blue arrows to navigate through the book or by following the navigation panel on the right side of the page.)
In a clinical trial, the objective is to obtain information about the effect of a treatment in a certain patient population who are likely to benefit from that treatment. However, the researchers cannot administer this treatment to the entire population. It would not be realistic for ethical, financial and often logistical reasons. Therefore, the clinical trial will be conducted only on a sample from the population of patients. This population sample should be representative of the whole population in order to allow the generalisations of the clinical trial findings.