5. Further Reading

  • Schulz KF, Grimes DA. Multiplicity in randomised trials II: sub-group and interim analyses. The Lancet May 2005, 365: 1591-95.

  • Lagakos SW. The challenge of sub-group analyses – reporting without distorting. N Engl J Med 354:16 April 2006. 1667-9.

  • Jennison, C. and Turnball, B.W (2000) Group Sequential Methods With Applications to Clinical Trials. Chapman & Hall/CRC Interdisciplinary Statistics

  • Sydes MR, Langley RE. Potential pitfalls in the design and reporting of clinical trials. Lancet Oncol. 2010 Jul;11(7):694-700. doi: 10.1016/S1470-2045(10)70041-3