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D

Data Merging

Data merging is a process that involves combining data from different sources, and providing users with a single view of these data.

For example:

  • data from different hospital sites within a clinical trial will be combined for analysis
  • data generated from entirely separate scientific studies might be combined if this will provide a better data set for analysis

Data Mining

Data mining is the practice of searching through existing large sets of data to find useful patterns or trends. Data mining can generate new hypotheses or new ideas for diagnosing, preventing, or treating diseases. It can, for example, lead to predictions for individual responses to medicines, or help with the design of completely new medicines.

The pharmaceutical industry uses sophisticated computer-driven data-mining techniques in an effort to extract information from the large amounts of chemical, biological, and clinical data available.

Data can be mined from clinical trial data sets, data from biobanks, or any other data set that is accessible “ for example, data sets held by public research organisations or insurance companies.

Data Monitoring Committee

Data Monitoring Committee

Dear Doctor letter

Dear Doctor letters are correspondence • often in the form of a mass mailing from the marketing authorisation holder of a human medicine or biologic • intended to alert doctors and other healthcare providers about important new or updated information regarding a marketed medicine or biologic.

Such information about medicinal products may emerge throughout a product™s life cycle.

Decentralised procedure

The decentralised procedure is a process for authorising medicines in more than one European Union member state at the same time.

Degradants

Chemical products formed from the breakdown of a medicine due to for example light, temperature, water, reaction with non-active substances, or container and closure systems, etc.

Delivery device

A device used for the delivery of a medicine or therapeutic agent via a specific route of administration (e.g. inhaler, dermal patch or infusion pump).

Delivery system

Medicine delivery systems encompass four main related aspects:

  1. Routes of delivery (ways in which the medications can be taken, such as orally, by injection, by inhalation, etc.).
  2. Delivery vehicles (dosage forms such as pills or slow-release granules).
  3. Chemical/biological properties of the active substance of the medicine (the cargo).
  4. Targeting strategies (delivery methods that deliver medicines to specific organs, tissues, tumours or structures inside of cells).

Det Nationale Institut for Kommuners og Regioners Analyse og Forskning

Danish Institute for Local and Regional Government Research http://www.kora.dk/temaer-paa-tvaers/sundhedsoekonomi/"

Deutsche Agentur für Health Technology Assessment



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